⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25979854 | 0.78 | — | — | |
| SCHEMBL18469362 | 0.77 | — | — | |
| SCHEMBL25784788 | 0.77 | — | — | |
| SCHEMBL15428338 | 0.75 | — | — | |
| SCHEMBL14724838 | 0.75 | — | — | |
| SCHEMBL22766001 | 0.74 | — | — | |
| SCHEMBL22631341 | 0.72 | — | — | |
| SCHEMBL18652736 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL21754979 | 0.69 | — | — | |
| SCHEMBL21725704 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200148716-A1 | AZIRIDINE SPINOSYN DERIVATIVES AND METHODS OF MAKING | AGRIMETIS, LLC (US) | 2020-05-14 | — | — | US | disclosed |
| US-10570165-B2 | Aziridine spinosyn derivatives and methods of making | AGRIMETIS, LLC (US) | 2020-02-25 | — | — | US | disclosed |
| US-10562896-B2 | 6-5 fused rings as C5a inhibitors | CHEMOCENTRYX, INC. (US) | 2020-02-18 | — | — | US | disclosed |