Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | KMO | O15229 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EIF4E | P06730 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070749 | 0.81 | SLC22A12 (0.63) | SLC22A12KMO | |
| SCHEMBL21727884 | 0.68 | SLC22A12 (0.46) | SLC22A12KMOEIF4E | |
| SCHEMBL21727868 | 0.68 | SLC22A12 (0.33) | SLC22A12 | |
| SCHEMBL12069337 | 0.65 | SLC22A12 (0.67) | SLC22A12KMOMAPTRIPK2KMT2A | |
| SCHEMBL10583164 | 0.64 | TDP1 (0.41) | ALDH1A1MAPTKMT2A | |
| SCHEMBL12070741 | 0.63 | SLC22A12 (0.63) | SLC22A12RIPK2 | |
| SCHEMBL12070366 | 0.63 | SLC22A12 (0.60) | SLC22A12KMOEIF4E | |
| SCHEMBL12070856 | 0.62 | SLC22A12 (0.62) | SLC22A12KMO | |
| SCHEMBL3322754 | 0.62 | AHR (0.52) | NPSR1KMOALDH1A1NPC1RAB9A | |
| SCHEMBL7541588 | 0.62 | KMO (0.48) | LMNANPSR1KMOGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611167-A1 | THIOACETATE COMPOUND AND METHODS OF USE | Ardea Biosciences, Inc. (US) | 2020-02-19 | — | — | EP | disclosed |