Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 15/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.40 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP8 | P40818 | 1/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12071486 | 0.83 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11MEN1KMT2A | |
| SCHEMBL9987685 | 0.76 | SLC22A12 (0.75) | SLC22A12SLC22A6SLC22A11MAPTABCG2 | |
| SCHEMBL9987800 | 0.75 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL12070773 | 0.73 | SLC22A12 (0.76) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL12070771 | 0.72 | SLC22A12 (0.92) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL16917824 | 0.72 | IMPDH2 (0.57) | SLC22A12KDM4EALDH1A1SLC22A6SLC22A11 | |
| SCHEMBL12070888 | 0.70 | SLC22A12 (1.00) | SLC22A12 | |
| SCHEMBL20020091 | 0.70 | SLC22A12 (0.78) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL19240229 | 0.68 | SLC22A12 (0.73) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL12069316 | 0.68 | SLC22A12 (0.73) | SLC22A12KDM4EALDH1A1HPGDSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611167-A1 | THIOACETATE COMPOUND AND METHODS OF USE | Ardea Biosciences, Inc. (US) | 2020-02-19 | — | — | EP | disclosed |