Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183126 | 0.89 | PDE10A (0.56) | MAPTKDM4EMEN1KMT2AATM | |
| SCHEMBL4049187 | 0.87 | SMN1; SMN2 (0.61) | MAPTKDM4EMEN1KMT2AATM | |
| SCHEMBL2172504 | 0.84 | MAPT (0.52) | MAPTKDM4EMEN1KMT2AATM | |
| SCHEMBL95067 | 0.82 | NPC1 (0.55) | MAPTATMPPARAPDE10ASMN1; SMN2 | |
| SCHEMBL31276816 | 0.82 | NPC1 (0.55) | MAPTATMPPARAPDE10ASMN1; SMN2 | |
| SCHEMBL2170238 | 0.82 | SMN1; SMN2 (0.50) | MAPTKDM4EMEN1KMT2APDK1 | |
| 2-Mercaptobenzothiazole SCHEMBL2172823 | 0.81 | PDE10A (0.49) | MAPTKDM4EMEN1KMT2AATM | |
| Methane SCHEMBL2171653 | 0.81 | PDE10A (0.49) | MAPTKDM4EMEN1KMT2AATM | |
| SCHEMBL9157816 | 0.79 | PPARA (0.53) | MAPTKDM4EMEN1KMT2AATM | |
| Benzo[D]Thiazole SCHEMBL25268299 | 0.79 | PDE10A (0.52) | MAPTKDM4EMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346956-A1 | ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES | Loctite (R & D) Limited (IE) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010046412-A1 | ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES | LOCTITE (R & D) LIMITED (IE) | 2010-04-29 | — | — | WO | disclosed |