Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | FBP1 | P09467 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | MC5R | P33032 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602939 | 0.86 | NPSR1 (0.65) | SMN1; SMN2NPSR1NPC1MEN1KMT2A | |
| SCHEMBL2337609 | 0.86 | NPSR1 (0.65) | SMN1; SMN2NPSR1NPC1MEN1KMT2A | |
| SCHEMBL2172827 | 0.82 | MAPT (0.58) | SMN1; SMN2NPSR1NPC1MEN1KMT2A | |
| SCHEMBL30106441 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2NPSR1NPC1KMT2ARAB9A | |
| SCHEMBL282023 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2NPSR1NPC1KMT2ARAB9A | |
| 2-Mercaptobenzothiazole SCHEMBL2170236 | 0.80 | MAPT (0.49) | SMN1; SMN2NPSR1NPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31731285 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2NPSR1NPC1KMT2ARAB9A | |
| SCHEMBL29368613 | 0.80 | ALDH1A1 (0.70) | SMN1; SMN2NPSR1NPC1RAB9AMAPT | |
| SCHEMBL316415 | 0.80 | ALDH1A1 (0.70) | SMN1; SMN2NPSR1NPC1RAB9AMAPT | |
| SCHEMBL2675923 | 0.77 | KEAP1 (0.65) | SMN1; SMN2NPSR1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346956-A1 | ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES | Loctite (R & D) Limited (IE) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010046412-A1 | ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES | LOCTITE (R & D) LIMITED (IE) | 2010-04-29 | — | — | WO | disclosed |