Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23169746 | 0.78 | DPP4 (0.53) | SLC7A5DPP4FAPDPP8DPP9 | |
| SCHEMBL1034777 | 0.78 | DPP4 (0.53) | SLC7A5DPP4FAPDPP8DPP9 | |
| SCHEMBL12285003 | 0.78 | DPP4 (0.53) | SLC7A5DPP4FAPDPP8DPP9 | |
| SCHEMBL21728686 | 0.77 | SLC7A5 (0.34) | SLC7A5DPP4FAPDPP8DPP9 | |
| SCHEMBL14136177 | 0.75 | — | — | |
| SCHEMBL21105596 | 0.70 | SLC7A5 (0.52) | SLC7A5DPP4FAPDPP8DPP9 | |
| SCHEMBL25100409 | 0.69 | PAX8 (0.33) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL1036161 | 0.68 | DPP4 (0.50) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL14151828 | 0.68 | DPP4 (0.50) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL12428127 | 0.68 | CTSC (0.41) | SLC7A5DPP4FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154997-B1 | AURISTATIN DERIVATIVES AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2020-02-19 | — | — | EP | disclosed |