Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18691855 | 0.87 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2MEN1KMT2AALDH1A1 | |
| SCHEMBL21728867 | 0.83 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2MEN1KMT2AALDH1A1 | |
| SCHEMBL12328966 | 0.83 | TSHR (0.52) | ZDHHC20ZDHHC2MEN1KMT2AALDH1A1 | |
| SCHEMBL4361183 | 0.83 | TSHR (0.52) | ZDHHC20ZDHHC2MEN1KMT2AALDH1A1 | |
| SCHEMBL12213321 | 0.83 | TSHR (0.52) | ZDHHC20ZDHHC2MEN1KMT2AALDH1A1 | |
| SCHEMBL12328384 | 0.83 | TSHR (0.52) | ZDHHC20ZDHHC2MEN1KMT2AALDH1A1 | |
| SCHEMBL10064051 | 0.81 | TSHR (0.54) | ZDHHC20ZDHHC2MEN1KMT2AALDH1A1 | |
| SCHEMBL18721196 | 0.81 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2MEN1KMT2AALDH1A1 | |
| SCHEMBL17035303 | 0.81 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2MEN1KMT2AALDH1A1 | |
| SCHEMBL21728862 | 0.81 | ZDHHC20 (0.44) | ZDHHC20ZDHHC2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3101171-B1 | MALODOR COUNTERACTING COMPOSITIONS | INT FLAVORS & FRAGRANCES INC (US) | 2020-02-19 | — | — | EP | disclosed |