Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419739 | 0.80 | HPGD (0.50) | ALDH1A1HSD17B10HTTL3MBTL1MAPT | |
| SCHEMBL9171979 | 0.76 | HSD17B10 (0.65) | ALDH1A1HSD17B10L3MBTL1MAPTHPGD | |
| SCHEMBL10824563 | 0.75 | HSD17B10 (0.67) | ALDH1A1HSD17B10L3MBTL1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL11024897 | 0.74 | HSD17B10 (0.69) | ALDH1A1HSD17B10HTTL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL11024113 | 0.74 | HSD17B10 (0.69) | ALDH1A1HSD17B10HTTL3MBTL1MAPT | |
| SCHEMBL14419738 | 0.74 | HPGD (0.52) | ALDH1A1HSD17B10HTTL3MBTL1MAPT | |
| SCHEMBL21729361 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HSD17B10HTTL3MBTL1MAPT | |
| SCHEMBL17122958 | 0.72 | UGCG (0.56) | ALDH1A1HSD17B10HTTL3MBTL1MAPT | |
| SCHEMBL19043464 | 0.72 | UGCG (0.56) | ALDH1A1HSD17B10HTTL3MBTL1MAPT | |
| SCHEMBL14960277 | 0.72 | UGCG (0.56) | ALDH1A1HSD17B10HTTL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611171-A1 | METHOD FOR SYNTHESIS OF ELIGLUSTAT AND INTERMEDIATE COMPOUNDS THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2020-02-19 | — | — | EP | disclosed |