Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513945 | 0.85 | KMT2A (0.53) | KMT2AALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL19794294 | 0.84 | ALDH1A1 (0.62) | KMT2AALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL1488779 | 0.82 | KMT2A (0.43) | KMT2AALDH1A1POLBTSHRFDPS | |
| SCHEMBL24527136 | 0.81 | KMT2A (0.42) | KMT2AALDH1A1POLBTSHRFDPS | |
| SCHEMBL20309584 | 0.77 | ALDH1A1 (0.36) | KMT2AALDH1A1POLBL3MBTL1TLR8 | |
| SCHEMBL20309522 | 0.77 | MAPT (0.39) | KMT2AALDH1A1POLBL3MBTL1TLR8 | |
| SCHEMBL24540417 | 0.76 | — | — | |
| SCHEMBL4772963 | 0.75 | KMT2A (0.59) | KMT2AALDH1A1POLBTSHRFDPS | |
| SCHEMBL8678546 | 0.75 | KMT2A (0.60) | KMT2AALDH1A1POLBTSHRFDPS | |
| SCHEMBL5438077 | 0.74 | ALDH1A1 (0.59) | KMT2AALDH1A1POLBCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035466-A1 | NOVEL SULFONEUREA COMPOUNDS | INFLAZOME LIMITED (IE) | 2020-02-20 | — | — | WO | disclosed |
| WO-2020035464-A1 | NOVEL SULFONAMIDEUREA COMPOUNDS | INFLAZOME LIMITED (IE) | 2020-02-20 | — | — | WO | disclosed |