Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 12/20 | 0.65 |
| ▸ | JAK1 | P23458 | 10/20 | 0.65 |
| ▸ | JAK3 | P52333 | 4/20 | 0.65 |
| ▸ | ABL1 | P00519 | 3/20 | 0.65 |
| ▸ | TYK2 | P29597 | 3/20 | 0.65 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.65 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.65 |
| ▸ | PAK4 | O96013 | 2/20 | 0.65 |
| ▸ | RET | P07949 | 2/20 | 0.65 |
| ▸ | LTK | P29376 | 2/20 | 0.65 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.65 |
| ▸ | CLK2 | P49760 | 2/20 | 0.65 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.65 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.65 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.65 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.65 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.65 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.65 |
| ▸ | CAMK1D | Q8IU85 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21729609 | 0.90 | JAK2 (0.66) | JAK2JAK1JAK3ABL1TYK2 | |
| SCHEMBL3003426 | 0.88 | JAK2 (0.60) | JAK2JAK1JAK3ABL1TYK2 | |
| SCHEMBL3003421 | 0.88 | JAK2 (0.60) | JAK2JAK1JAK3ABL1TYK2 | |
| SCHEMBL16085076 | 0.88 | JAK2 (0.64) | JAK2JAK1JAK3ABL1TYK2 | |
| SCHEMBL25603410 | 0.88 | JAK2 (0.64) | JAK2JAK1JAK3ABL1TYK2 | |
| SCHEMBL20805679 | 0.88 | JAK2 (0.69) | JAK2JAK1JAK3ABL1TYK2 | |
| SCHEMBL27200381 | 0.88 | JAK2 (0.66) | JAK2JAK1JAK3ABL1TYK2 | |
| SCHEMBL26429919 | 0.88 | JAK2 (0.66) | JAK2JAK1JAK3ABL1TYK2 | |
| SCHEMBL27835856 | 0.88 | JAK2 (0.66) | JAK2JAK1JAK3ABL1TYK2 | |
| SCHEMBL25566894 | 0.87 | JAK2 (0.66) | JAK2JAK1JAK3ABL1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271982-A1 | CODRUG THAT DISINTEGRATES IN INTESTINE, PREPARATION THEREFOR, AND USE THEREOF | SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| US-20230271982-A1 | CODRUG THAT DISINTEGRATES IN INTESTINE, PREPARATION THEREFOR, AND USE THEREOF | SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| US-20230115871-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2023-04-13 | — | — | US | disclosed |
| WO-2020034987-A1 | PRODRUG CONTAINING GLUCURONIDE DERIVATIVE OF JAK INHIBITOR, PREPARATION METHOD THEREFOR, AND USES THEREOF | 江苏豪森药业集团有限公司 | 2020-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230115871-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | CD2BP2, EPCAM, CD74 | JAK2 3482/4885JAK1 3804/4885JAK3 3680/4885 |
| US-20230271982-A1 | CODRUG THAT DISINTEGRATES IN INTESTINE, PREPARATION THEREFOR, AND USE THEREOF | VIP, SI, PDCD5 | JAK2 4173/4885JAK1 2922/4885JAK3 3340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.