⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19589446 | 0.80 | — | — | |
| SCHEMBL2621618 | 0.79 | IDO1 (0.37) | — | |
| SCHEMBL22515608 | 0.77 | IDO1 (0.33) | — | |
| SCHEMBL20458029 | 0.75 | — | — | |
| SCHEMBL22845192 | 0.75 | — | — | |
| SCHEMBL20272644 | 0.75 | — | — | |
| SCHEMBL26772340 | 0.75 | — | — | |
| SCHEMBL24991561 | 0.72 | — | — | |
| SCHEMBL21419598 | 0.72 | ACHE (0.36) | — | |
| SCHEMBL24631048 | 0.71 | IDO1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10988491-B2 | Degradable polymers of a cyclic silyl ether and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-04-27 | — | — | US | disclosed |
| US-20200055879-A1 | DEGRADABLE POLYMERS OF A CYCLIC SILYL ETHER AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-02-20 | — | — | US | disclosed |