Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.36 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10864320 | 0.84 | MEN1 (0.46) | ALDH1A1KMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL8497069 | 0.79 | NPC1 (0.41) | ALDH1A1KMT2AMEN1ELANELMNA | |
| SCHEMBL27817130 | 0.78 | MEN1 (0.41) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL31619553 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL9594468 | 0.77 | MEN1 (0.34) | ALDH1A1KDM4EKMT2AMEN1ELANE | |
| SCHEMBL2828217 | 0.76 | MEN1 (0.43) | ALDH1A1KDM4EKMT2AMEN1L3MBTL1 | |
| SCHEMBL6246649 | 0.74 | KMT2A (0.60) | ALDH1A1KDM4EKMT2AMEN1L3MBTL1 | |
| SCHEMBL3164058 | 0.74 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2ALMNAL3MBTL1 | |
| SCHEMBL491764 | 0.73 | NAPRT (0.50) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL8416284 | 0.72 | ALDH1A1 (0.51) | ALDH1A1KDM4EKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102271508-A | Pyrido (4,3-b) indoles containing rigid moieties | — | 2011-12-07 | — | — | CN | disclosed |
| EP-2346332-A1 | PYRIDO (4,3-B) INDOLES CONTAINING RIGID MOIETIES | Medivation Technologies, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010051501-A1 | PYRIDO (4,3-B) INDOLES CONTAINING RIGID MOIETIES | MEDIVATION TECHNOLOGIES, INC. (US) | 2010-05-06 | — | — | WO | disclosed |