Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23150535 | 1.00 | MGLL (0.72) | MGLL | |
| SCHEMBL21723746 | 1.00 | MGLL (0.72) | MGLL | |
| SCHEMBL23150534 | 1.00 | MGLL (0.72) | MGLL | |
| SCHEMBL23176601 | 1.00 | MGLL (0.72) | MGLL | |
| SCHEMBL23148888 | 0.95 | MGLL (0.69) | MGLL | |
| SCHEMBL29616634 | 0.92 | MGLL (0.67) | MGLL | |
| SCHEMBL22488645 | 0.92 | MGLL (0.67) | MGLL | |
| SCHEMBL31071596 | 0.92 | MGLL (0.67) | MGLL | |
| SCHEMBL23176453 | 0.91 | MGLL (0.75) | MGLL | |
| SCHEMBL23152344 | 0.91 | MGLL (0.75) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035425-A1 | NEW HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-02-20 | — | — | WO | disclosed |
| WO-2020035424-A1 | NEW HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-02-20 | — | — | WO | disclosed |