Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23149085 | 1.00 | MGLL (0.65) | MGLL | |
| SCHEMBL22488095 | 1.00 | MGLL (0.65) | MGLL | |
| SCHEMBL30775908 | 0.91 | MGLL (0.55) | MGLL | |
| SCHEMBL30775780 | 0.91 | MGLL (0.55) | MGLL | |
| SCHEMBL30775809 | 0.90 | MGLL (0.56) | MGLL | |
| SCHEMBL27371965 | 0.89 | MGLL (0.62) | MGLL | |
| SCHEMBL27373156 | 0.89 | MGLL (0.62) | MGLL | |
| SCHEMBL27372429 | 0.88 | MGLL (0.54) | MGLL | |
| SCHEMBL22462763 | 0.87 | MGLL (0.66) | MGLL | |
| SCHEMBL21730850 | 0.87 | MGLL (0.66) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035425-A1 | NEW HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-02-20 | — | — | WO | disclosed |
| WO-2020035424-A1 | NEW HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-02-20 | — | — | WO | disclosed |