Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21722872 | 1.00 | MGLL (0.61) | MGLL | |
| SCHEMBL23149037 | 1.00 | MGLL (0.61) | MGLL | |
| SCHEMBL21730887 | 0.94 | MGLL (0.63) | MGLL | |
| SCHEMBL23853048 | 0.89 | MGLL (0.56) | MGLL | |
| SCHEMBL21723095 | 0.89 | MGLL (0.60) | MGLL | |
| SCHEMBL29616491 | 0.89 | MGLL (0.60) | MGLL | |
| SCHEMBL21730909 | 0.87 | MGLL (0.58) | MGLL | |
| SCHEMBL24095491 | 0.87 | MGLL (0.56) | MGLL | |
| SCHEMBL25784975 | 0.87 | MGLL (0.56) | MGLL | |
| SCHEMBL24095474 | 0.86 | MGLL (0.59) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3837263-B1 | NEW HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2024-07-03 | — | — | EP | disclosed |
| WO-2020035424-A1 | NEW HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-02-20 | — | — | WO | disclosed |
| WO-2020035425-A1 | NEW HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-02-20 | — | — | WO | disclosed |