Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.43 |
| ▸ | PGR | P06401 | 3/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23521842 | 0.86 | KDM4E (0.45) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL23543166 | 0.86 | KDM4E (0.45) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL29662251 | 0.86 | KDM4E (0.45) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL23521838 | 0.86 | KDM4E (0.45) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL23521919 | 0.86 | KDM4E (0.45) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL30116302 | 0.77 | NR3C1 (0.40) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL27205350 | 0.77 | NR3C1 (0.40) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL24737106 | 0.77 | NR3C1 (0.40) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL27176496 | 0.77 | NR3C1 (0.40) | KDM4EMAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL23522145 | 0.76 | KDM4E (0.51) | KDM4EMAPTRAB9AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020036386-A1 | ISOINDOLIN-1-ON DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT FOR PREVENTING OR TREATING CANCER | 한국화학연구원 | 2020-02-20 | — | — | WO | disclosed |