SCHEMBL21732473

SCHEMBL21732473

C=C(C)Oc1ccccc1Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 9/20 0.49
DRD1 P21728 3/20 0.49
DRD2 P14416 2/20 0.49
DRD4 P21917 2/20 0.49
DRD5 P21918 2/20 0.49
TP53 P04637 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
TSHR P16473 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
DRD3 P35462 2/20 0.46
LMNA P02545 1/20 0.46
SLC5A1 P13866 1/20 0.43
SLC5A2 P31639 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30778391 0.85 HRH1 (0.47) HRH1DRD1DRD2DRD4DRD5
SCHEMBL4344154 0.85 HRH1 (0.47) HRH1DRD1DRD2DRD4DRD5
SCHEMBL531084 0.82 PTGS2 (0.54) HRH1DRD1DRD2DRD4DRD5
SCHEMBL5478147 0.78 HPGD (0.50) HRH1DRD1DRD2DRD4DRD5
SCHEMBL5478146 0.78 HPGD (0.50) HRH1DRD1DRD2DRD4DRD5
SCHEMBL28353997 0.78 HRH1 (0.44) HRH1DRD1DRD2DRD4DRD5
SCHEMBL1345320 0.76 HRH1 (0.51) HRH1DRD1DRD2DRD4DRD5
SCHEMBL27644538 0.75 HPGD (0.51) HRH1DRD1DRD2DRD4DRD5
SCHEMBL11607227 0.75 HPGD (0.47) HRH1DRD1DRD2DRD4DRD5
SCHEMBL7597025 0.75 HPGD (0.51) HRH1DRD1DRD2DRD4DRD5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020036314-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING SAME 주식회사 엘지화학 2020-02-20 WO disclosed