SCHEMBL21733016

SCHEMBL21733016

CC(C)(C)OC(=O)N1CCC(c2nc(C3=NOC(c4c(F)cccc4F)C3)cs2)CC1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20542436 1.00 FAAH (0.60) FAAH
SCHEMBL28860653 0.94 FAAH (0.56) FAAH
SCHEMBL2000000 0.93 FAAH (0.54) FAAH
SCHEMBL251806 0.90 FAAH (0.61) FAAH
SCHEMBL14141823 0.90 FAAH (0.54) FAAH
SCHEMBL14141911 0.90 FAAH (0.54) FAAH
SCHEMBL14786226 0.90 FAAH (0.55) FAAH
SCHEMBL28788508 0.90 FAAH (0.64) FAAH
SCHEMBL20797285 0.88 FAAH (0.61) FAAH
SCHEMBL20541375 0.88 FAAH (0.51) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4058451-B1 1-(4-(4-(5-PHENYL-4,5-DIHYDROISOXAZOL-3-YL)THIAZOL-2-YL)PIPERIDIN-1-YL)-ETHAN-1-ONE DERIVATIVES AND RELATED COMPOUNDS AS FUNGICIDES FOR CROP PROTECTION PI INDUSTRIES LTD (IN) 2024-03-06 EP disclosed
US-20230031192-A1 NOVEL SUBSTITUTED 6- MEMBERED HETEROARYL PIPERIDINYL ETHANONES PI INDUSTRIES LTD. (IN) 2023-02-02 US disclosed
CN-114761403-A 1- (4- (4- (5-phenyl-4, 5-dihydroisoxazol-3-yl) thiazol-2-yl) piperidin-1-yl) -ethan-1-one derivatives and related compounds as crop protection fungicides PI工业有限公司 2022-07-15 CN disclosed
WO-2021094905-A1 1 -(4-(4-(5-PHENYL-4,5-DIHYDROISOXAZOL-3-YL)THIAZOL-2-YL)PIPERIDIN-1 -YL)-ETHAN-1 -ONE DERIVATIVES AND RELATED COMPOUNDS AS FUNGICIDES FOR CROP PROTECTION PI INDUSTRIES LTD. (IN) 2021-05-20 WO disclosed
CN-111655687-A Novel fungicidal heterocyclic compounds PI工业有限公司 2020-09-11 CN disclosed
US-20200281202-A1 NOVEL FUNGICIDAL HETEROCYCLIC COMPOUNDS PI INDUSTRIES LTD. (IN) 2020-09-10 US disclosed
WO-2020034992-A1 FUSED HETEROCYCLE STRUCTURE-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATIONS THEREOF, AND FUNGICIDE 华中师范大学 2020-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230031192-A1 NOVEL SUBSTITUTED 6- MEMBERED HETEROARYL PIPERIDINYL ETHANONES CCNK, CYP1B1, CYP1A1 FAAH 1346/4885
US-20200281202-A1 NOVEL FUNGICIDAL HETEROCYCLIC COMPOUNDS CYP1B1, CYP1A1, CYP51A1 FAAH 1647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.