Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 9/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | HTR2C | P28335 | 6/20 | 0.42 |
| ▸ | HTR2B | P41595 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430529 | 0.86 | KMO (0.64) | KMOCYP11B2HTR2AHTR2CHTR2B | |
| SCHEMBL14155060 | 0.83 | KMO (0.66) | KMOCYP11B2HTR2AHTR2CHTR2B | |
| SCHEMBL13607530 | 0.80 | KMO (0.60) | KMOHTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL16101274 | 0.79 | HTR2A (0.66) | KMOHTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL6181444 | 0.79 | KMO (0.59) | KMOHTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL217944 | 0.79 | HTR2A (0.45) | KMOHTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL31039602 | 0.79 | HTR2A (0.45) | KMOHTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL29520619 | 0.79 | HTR2A (0.65) | KMOTSHRCYP11B2HTR2AHTR2C | |
| SCHEMBL30381343 | 0.79 | KMO (0.59) | KMOHTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL8253090 | 0.77 | KMO (0.70) | KMOCYP11B2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402797-B1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2020-02-19 | — | — | EP | disclosed |