Bis(2-Ethylhexyl)Phthalate

Bis(2-Ethylhexyl)Phthalate

SCHEMBL21733281

CCCCC(CC)COC(=O)c1ccccc1C(=O)OC[C@H](CC)CCCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 1.00
CYP3A4 P08684 5/20 1.00
CA2 P00918 1/20 1.00
PRSS1 P07477 1/20 0.89
PRSS2 P07478 1/20 0.89
PRSS3 P35030 1/20 0.89
LMNA P02545 4/20 0.84
TSHR P16473 9/20 0.72
MAPK1 P28482 5/20 0.72
HSD17B10 Q99714 2/20 0.60
TDP1 Q9NUW8 4/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
TP53 P04637 1/20 0.57
ATM Q13315 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bis(2-Ethylhexyl)Phthalate SCHEMBL29411299 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4CA2PRSS1PRSS2
Bis(2-Ethylhexyl) Phthalate SCHEMBL2864306 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4CA2PRSS1PRSS2
Bis(2-Ethylhexyl) Phthalate SCHEMBL29351619 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4CA2PRSS1PRSS2
Bis(2-Ethylhexyl) Phthalate SCHEMBL20271 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4CA2PRSS1PRSS2
Bis(2-Ethylhexyl) Phthalate SCHEMBL74067 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4CA2PRSS1PRSS2
Bis(2-Ethylhexyl) Phthalate SCHEMBL8397045 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4CA2PRSS1PRSS2
Bis(2-Ethylhexyl) Phthalate SCHEMBL14892433 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4CA2PRSS1PRSS2
Bis(2-Ethylhexyl) Phthalate SCHEMBL22190333 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4CA2PRSS1PRSS2
Bis(2-Ethylhexyl) Phthalate SCHEMBL9017840 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4CA2PRSS1PRSS2
Bis(2-Ethylhexyl) Phthalate SCHEMBL4602015 0.98 ALDH1A1 (0.97) ALDH1A1CYP3A4CA2PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200054933-A1 MAINTENANCE METHOD OF BOWLING BALL, PLASTICIZER YAMADA YUTAKA (JP) 2020-02-20 US disclosed