Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097769 | 0.68 | MEN1 (0.59) | KMT2AMEN1BRD4PNPPARP1 | |
| SCHEMBL806161 | 0.66 | KMT2A (0.45) | KMT2AMEN1BRD4PNPPARP1 | |
| SCHEMBL11622684 | 0.64 | NOS3 (0.32) | KMT2AMEN1BRD4ALDH1A1 | |
| SCHEMBL30834488 | 0.64 | MEN1 (0.54) | KMT2AMEN1BRD4PNPPARP1 | |
| SCHEMBL21733507 | 0.64 | MEN1 (0.54) | KMT2AMEN1BRD4PNPPARP1 | |
| SCHEMBL31460305 | 0.64 | MEN1 (0.54) | KMT2AMEN1BRD4PNPPARP1 | |
| SCHEMBL6581511 | 0.62 | MEN1 (0.51) | KMT2AMEN1BRD4PNPPARP1 | |
| SCHEMBL24854412 | 0.61 | MEN1 (0.51) | KMT2AMEN1BRD4PNPPARP1 | |
| SCHEMBL21733361 | 0.61 | MEN1 (0.51) | KMT2AMEN1BRD4PNPPARP1 | |
| SCHEMBL13186667 | 0.61 | MEN1 (1.00) | KMT2AMEN1PNPPARP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035031-A1 | FUSED RING COMPOUNDS | GENENTECH, INC. (US) | 2020-02-20 | — | — | WO | disclosed |