Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 7/20 | 0.35 |
| ▸ | CDK2 | P24941 | 7/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21024008 | 0.67 | PLK1 (0.45) | — | |
| SCHEMBL6333956 | 0.62 | CCNA2 (0.41) | CCNA2CDK2CCNA1GRM4 | |
| SCHEMBL9221790 | 0.60 | CCNA2 (0.47) | CCNA2CDK2CCNA1 | |
| SCHEMBL2377273 | 0.59 | CDK8 (0.46) | CCNA2CDK2CCNA1GRM4AKT1 | |
| SCHEMBL1395016 | 0.58 | GRM4 (0.41) | CCNA2CDK2CCNA1GRM4 | |
| SCHEMBL6476656 | 0.58 | GRM4 (0.38) | CCNA2CDK2CCNA1GRM4 | |
| SCHEMBL9533873 | 0.58 | PLK1 (0.54) | CCNA2CDK2CCNA1GRM4 | |
| SCHEMBL6837080 | 0.57 | PRKACA (0.36) | CCNA2CDK2CCNA1GRM4 | |
| SCHEMBL17262729 | 0.57 | CDC7 (0.42) | CCNA2CDK2CCNA1AKT1 | |
| Water SCHEMBL6036229 | 0.57 | GRM4 (0.40) | CCNA2CDK2CCNA1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035031-A1 | FUSED RING COMPOUNDS | GENENTECH, INC. (US) | 2020-02-20 | — | — | WO | disclosed |