Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2454268 | 1.00 | — | — | |
| Bicarbonate SCHEMBL21638664 | 1.00 | CA4 (0.39) | — | |
| Bicarbonate SCHEMBL570557 | 1.00 | — | — | |
| Bicarbonate SCHEMBL873152 | 1.00 | CA4 (0.39) | — | |
| Bicarbonate SCHEMBL176208 | 0.95 | CA4 (0.42) | — | |
| Bicarbonate SCHEMBL28139629 | 0.95 | CA4 (0.42) | — | |
| Bicarbonate SCHEMBL120120 | 0.95 | — | — | |
| Bicarbonate SCHEMBL6577710 | 0.91 | CA1 (0.33) | — | |
| Bicarbonate SCHEMBL9950136 | 0.90 | — | — | |
| Bicarbonate SCHEMBL29171483 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10568957-B2 | Rotavirus vaccine compositions and process for preparing the same | BHARAT BIOTECH INTERNATIONAL LTD. (IN) | 2020-02-25 | — | — | US | claimed |
| EP-2945650-B1 | ROTAVIRUS VACCINE COMPOSITIONS AND PROCESS FOR PREPARING THE SAME | BHARAT BIOTECH INT LTD (IN) | 2023-07-05 | — | — | EP | disclosed |