Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL21734207 | 1.00 | — | — | |
| Bicarbonate SCHEMBL2454268 | 1.00 | — | — | |
| Bicarbonate SCHEMBL21638664 | 1.00 | CA4 (0.39) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL570557 | 1.00 | — | — | |
| Bicarbonate SCHEMBL176208 | 0.95 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL28139629 | 0.95 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL120120 | 0.95 | — | — | |
| Bicarbonate SCHEMBL6577710 | 0.91 | CA1 (0.33) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL9950136 | 0.90 | — | — | |
| Bicarbonate SCHEMBL29171483 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096219-A1 | CURABLE SILICONE COMPOSITION AND USES THEREOF | ROGERS CORPORATION (US) | 2025-05-08 | — | — | WO | claimed |
| WO-2025006103-A1 | COMPRESSIBLE SILICONE FOAM AND METHOD FOR THE MANUFACTURE THEREOF | ROGERS CORPORATION (US) | 2025-01-02 | — | — | WO | claimed |
| US-20240425660-A1 | COMPRESSIBLE SILICONE FOAM AND METHOD FOR THE MANUFACTURE THEREOF | ROGERS CORP (US) | 2024-12-26 | — | — | US | claimed |
| US-12119467-B2 | Composite thermal management sheet, method of manufacture, and articles using the same | ROGERS CORPORATION (US) | 2024-10-15 | — | — | US | claimed |
| EP-4347248-A1 | MULTILAYER COMPOSITE WITH THERMAL BARRIER PROPERTIES | Saint-Gobain Performance Plastics Corporation (US) | 2024-04-10 | — | — | EP | claimed |
| EP-4347695-A1 | FOAM LAYER WITH THERMAL BARRIER PROPERTIES | Saint-Gobain Performance Plastics Corporation (US) | 2024-04-10 | — | — | EP | claimed |
| US-20240088483-A1 | THERMALLY INSULATING MULTILAYER SHEET, METHOD OF MANUFACTURE, AND ARTICLES USING THE SAME | ROGERS CORP (US) | 2024-03-14 | — | — | US | claimed |
| US-20220388291-A1 | MULTILAYER COMPOSITE WITH THERMAL BARRIER PROPERTIES | SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION | 2022-12-08 | — | — | US | claimed |
| WO-2022256781-A1 | MULTILAYER COMPOSITE WITH THERMAL BARRIER PROPERTIES | SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) | 2022-12-08 | — | — | WO | claimed |
| US-20220389152-A1 | FOAM LAYER WITH THERMAL BARRIER PROPERTIES | SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION | 2022-12-08 | — | — | US | claimed |
| EP-1218322-A1 | CATALYST COMPOSITION AND PROCESS FOR MAKING THE COMPOSITION | Phillips Petroleum Company (US) | 2002-07-03 | — | — | EP | claimed |
| US-20020051794-A1 | Novel parenteral vaccine formulations and uses thereof | ALK-ABELLO A/S | 2002-05-02 | — | — | US | claimed |
| US-6369000-B1 | IMPREGNATING ALUMINA WITH A MELTED METAL COMPOUND, CALCINING, DOES NOT INVOLVE PHYSICAL MIXING OR COPRECIPITATION | PHILLIPS PETROLEUM COMPANY | 2002-04-09 | — | — | US | claimed |
| WO-2002011760-A1 | PARENTERAL VACCINE FORMULATIONS AND USES THEREOF | Alk-Abelló A/S (DK) | 2002-02-14 | — | — | WO | claimed |
| US-20010046943-A1 | HYDROCARBON HYDROGENATION CATALYST AND PROCESS | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2001-11-29 | — | — | US | claimed |
| WO-2001019763-A1 | CATALYST COMPOSITION AND PROCESS FOR MAKING THE COMPOSITION | PHILLIPS PETROLEUM COMPANY (US) | 2001-03-22 | — | — | WO | claimed |
| WO-2001019514-A1 | PROCESS FOR PRODUCING A METAL ALUMINATE CATALYST SUPPORT | PHILIPS PETROLEUM COMPANY (US) | 2001-03-22 | — | — | WO | claimed |
| US-5627303-A | ALDOL CONDENSATION OF ACETONE, CALCINED MAGNESIUM/ALUMINUM MIXED OXIDE CATALYST | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-05-06 | — | — | US | claimed |
| EP-0640387-A1 | Preparation of isophorone using a magnesium/aluminum mixed oxide catalyst | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-03-01 | — | — | EP | claimed |
| EP-0640388-A1 | Magnesium/aluminum mixed oxide catalysts and their use in the production of aminoethers | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-03-01 | — | — | EP | claimed |