Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ECE1 | P42892 | 4/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25962978 | 0.89 | MAPT (0.41) | MAPTECE1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL23682572 | 0.82 | MAPT (0.40) | MAPTECE1HDAC2POLBTDP1 | |
| SCHEMBL13385188 | 0.79 | MAPT (0.46) | MAPTHDAC2POLBKDM1APIK3CD | |
| SCHEMBL8277450 | 0.79 | MAPT (0.46) | MAPTHDAC2POLBKDM1APIK3CD | |
| SCHEMBL20349682 | 0.79 | MAPT (0.46) | MAPTHDAC2POLBKDM1APIK3CD | |
| SCHEMBL16941948 | 0.79 | MAPT (0.46) | MAPTHDAC2POLBKDM1APIK3CD | |
| SCHEMBL3042873 | 0.77 | SLC1A3 (0.43) | MAPTECE1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL24696823 | 0.77 | SLC1A3 (0.43) | MAPTECE1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL24568173 | 0.77 | MAPT (0.43) | MAPTHDAC2POLBKDM1APIK3CD | |
| SCHEMBL16139219 | 0.77 | MAPT (0.43) | MAPTHDAC2POLBKDM1APIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827906-B2 | Adeno-associated virus (AAV) clade f vector and uses therefor | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827906-B2 | Adeno-associated virus (AAV) clade f vector and uses therefor | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2023-11-28 | — | — | US | disclosed |
| US-20200056159-A1 | NOVEL ADENO-ASSOCIATED VIRUS (AAV) CLADE F VECTOR AND USES THEREFOR | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200056159-A1 | NOVEL ADENO-ASSOCIATED VIRUS (AAV) CLADE F VECTOR AND USES THEREFOR | VSIG8, ASNS, FARSB | MAPT 2146/4885ECE1 3685/4885SLC1A3 334/4885 |
| US-11827906-B2 | Adeno-associated virus (AAV) clade f vector and uses therefor | ASNS, VSIG8, FARSB | MAPT 1839/4885ECE1 3602/4885SLC1A3 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.