SCHEMBL21734394

SCHEMBL21734394

CC1(C)c2cccc(P(c3ccccc3)c3ccc(N)cc3)c2Oc2c(P(c3ccccc3)c3ccc(N)cc3)cccc21

nearest known ligand 0.83

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 2/20 0.83
CYP3A4 P08684 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21734356 0.96 DRD1 (0.74) DRD1
SCHEMBL29359136 0.91 DRD1 (1.00) DRD1CYP3A4TDP1
SCHEMBL29351143 0.91 DRD1 (1.00) DRD1CYP3A4TDP1
SCHEMBL6953 0.91 DRD1 (1.00) DRD1CYP3A4TDP1
SCHEMBL25373924 0.90 DRD1 (0.97) DRD1CYP3A4TDP1
SCHEMBL38656170 0.90 DRD1 (0.97) DRD1CYP3A4TDP1
SCHEMBL15209802 0.90 DRD1 (0.97) DRD1CYP3A4TDP1
Ammonia Solution, Strong SCHEMBL19127610 0.90 DRD1 (0.97) DRD1CYP3A4TDP1
SCHEMBL17743663 0.90 DRD1 (0.97) DRD1CYP3A4TDP1
Hydrochloric Acid SCHEMBL29821183 0.90 DRD1 (0.97) DRD1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020034477-A1 POROUS ORGANIC CAGE LIGAND CONTAINING P AND N, PREPARATION THEREFOR AND USE THEREOF 中国科学院大连化学物理研究所 2020-02-20 WO disclosed
WO-2020034476-A1 POROUS ORGANIC CAGE LIGAND CONTAINING P AND N AND COMPLEX CATALYST AND APPLICATION 中国科学院大连化学物理研究所 2020-02-20 WO disclosed