SCHEMBL29359136

SCHEMBL29359136

CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 2/20 1.00
CYP3A4 P08684 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351143 1.00 DRD1 (1.00) DRD1CYP3A4TDP1ESR1ESR2
SCHEMBL6953 1.00 DRD1 (1.00) DRD1CYP3A4TDP1ESR1ESR2
Hydrochloric Acid SCHEMBL29821183 0.98 DRD1 (0.97) DRD1CYP3A4TDP1
Ammonia Solution, Strong SCHEMBL19127610 0.98 DRD1 (0.97) DRD1CYP3A4TDP1
Hydrochloric Acid SCHEMBL28990395 0.98 DRD1 (0.97) DRD1CYP3A4TDP1
SCHEMBL25373924 0.98 DRD1 (0.97) DRD1CYP3A4TDP1
SCHEMBL17743663 0.98 DRD1 (0.97) DRD1CYP3A4TDP1ESR1ESR2
SCHEMBL15209802 0.98 DRD1 (0.97) DRD1CYP3A4TDP1
SCHEMBL38656170 0.98 DRD1 (0.97) DRD1CYP3A4TDP1
Phosphine SCHEMBL28527853 0.98 DRD1 (0.97) DRD1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008798-A1 PALLADIUM CATALYZED SYNTHESIS OF AMINOALDEHYDE INTERMEDIATES HOFFMANN-LA ROCHE INC. (US) 2026-01-08 US claimed
WO-2025122555-A1 S1P 1 RECEPTOR AGONISTS AND USES THEREOF VALO HEALTH, INC. (US) 2025-06-12 WO claimed
CN-119528886-A Shearing inhibitor for pre-miR-21 post-transcriptional processing and preparation method and application thereof 广东工业大学 2025-02-28 CN claimed
EP-4188551-B1 ARYL SUBSTITUTED PYRROLO-PYRIDINONES AND THERAPEUTIC USES THEREOF BAYER AG (DE) 2024-12-18 EP claimed
EP-4441043-A1 SOLID STATE FORMS OF DEUCRAVACITINIB, DEUCRAVACITINIB HCL AND PROCESS FOR PREPARATION OF DEUCRAVACITINIB AND INTERMEDIATES Teva Czech Industries s.r.o (CZ) 2024-10-09 EP claimed
CN-118666745-A Preparation method of C2-site arylation or alkenylation quinoline compound 郑州大学 2024-09-20 CN claimed
CN-118125926-A Dimethylaminoethoxy ethanol methyl synthesis process and system 安徽恒光聚氨酯材料有限公司 2024-06-04 CN claimed
EP-4359401-A1 PROCESS FOR PREPARING EGFR INHIBITORS Blueprint Medicines Corporation (US) 2024-05-01 EP claimed
CN-117917412-A Process for preparing chiral lactones 帝斯曼知识产权资产管理有限公司 2024-04-23 CN claimed
WO-2024069646-A1 IMPROVED PROCESS FOR THE PREPARATION OF RISDIPLAM AND ITS INTERMEDIATES NATCO PHARMA LIMITED (IN) 2024-04-04 WO claimed
EP-3383838-B1 PROCESS FOR THE CATALYTIC REVERSIBLE UNSATURATED HYDROCARBON-NITRILE INTERCONVERSION STUDIENGESELLSCHAFT KOHLE GGMBH (DE) 2023-10-25 EP claimed
US-20230322767-A1 ARYL SUBSTITUTED PYRROLO-PYRIDINONES AND THERAPEUTIC USES THEREOF THE BROAD INSTITUTE, INC. 2023-10-12 US claimed
CN-112321526-B Method for synthesizing heteroaromatic methylamine compound through redox-decarboxylation coupling reaction 西北师范大学 2023-09-22 CN claimed
CN-116802187-A Organometallic compounds 优米科尔股份公司及两合公司 2023-09-22 CN claimed
CN-116724021-A Synthesis of polyfluorinated aryl and heteroaryl carboxamides 巴斯夫欧洲公司 2023-09-08 CN claimed
WO-2023102085-A1 SOLID STATE FORMS OF DEUCRAVACITINIB, DEUCRAVACITINIB HCL AND PROCESS FOR PREPARATION OF DEUCRAVACITINIB AND INTERMEDIATES TEVA CZECH INDUSTRIES S.R.O. (CZ) 2023-06-08 WO claimed
EP-4188551-A1 ARYL SUBSTITUTED PYRROLO-PYRIDINONES AND THERAPEUTIC USES THEREOF Bayer Aktiengesellschaft (DE) 2023-06-07 EP claimed
EP-4132902-A1 PD-CATALYZED AMINATION OF FLUORINATED ARYL CHLORIDES BASF SE (DE) 2023-02-15 EP claimed
WO-2022271801-A1 PROCESS FOR PREPARING EGFR INHIBITORS BLUEPRINT MEDICINES CORPORATION (US) 2022-12-29 WO claimed
CN-115322176-A 2, 3-dihydrobenzofuranyl substituted 1H-indazole compound and preparation and application thereof 温州医科大学 2022-11-11 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008798-A1 PALLADIUM CATALYZED SYNTHESIS OF AMINOALDEHYDE INTERMEDIATES ADH1C, AOC1, AOC2 DRD1 266/4885CYP3A4 3031/4885TDP1 332/4885
US-20230322767-A1 ARYL SUBSTITUTED PYRROLO-PYRIDINONES AND THERAPEUTIC USES THEREOF PNPO, THPO, PAH DRD1 4470/4885CYP3A4 41/4885TDP1 3041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.