SCHEMBL2173479

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2785911	1.00	PTPN1 (0.47)	PTPN1CISD1MAOBCA9GAA
	SCHEMBL2172007	0.89	MCL1 (0.44)	PTPN1MYCMAXS1PR1S1PR3
	SCHEMBL2171003	0.89	AKR1B1 (0.47)	PPARGS1PR1S1PR3MCL1ESR1
	SCHEMBL2786612	0.89	MCL1 (0.44)	PTPN1MYCMAXS1PR1S1PR3
	SCHEMBL2784557	0.89	AKR1B1 (0.47)	PPARGS1PR1S1PR3MCL1ESR1
	SCHEMBL2173147	0.88	MCL1 (0.57)	PTPN1MAOBS1PR1S1PR3MCL1
	SCHEMBL2172867	0.88	MCL1 (0.44)	PTPN1MCL1ALDH1A1HPGDMEN1
	SCHEMBL2784736	0.88	MCL1 (0.57)	PTPN1MAOBS1PR1S1PR3MCL1
	SCHEMBL2786112	0.87	AURKA (0.43)	PTPN1CA9PPARGESR1ESR2
	SCHEMBL2172237	0.87	AURKA (0.43)	PTPN1CA9PPARGESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.