SCHEMBL21735745

SCHEMBL21735745

CC1(C)c2cccc(P(Oc3ccccc3)Oc3ccc(N)cc3)c2Oc2c(P(Oc3ccccc3)Oc3ccc(N)cc3)cccc21

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 2/20 0.56
MAOA P21397 1/20 0.37
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
NLRP3 Q96P20 1/20 0.32
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MITF O75030 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
GFER P55789 1/20 0.32
NLRP1 Q9C000 1/20 0.32
NOD2 Q9HC29 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21735756 0.96 DRD1 (0.52) DRD1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL2174276 0.92 DRD1 (0.65) DRD1
SCHEMBL21734391 0.87 DRD1 (0.44) DRD1
SCHEMBL21734395 0.84 DRD1 (0.52) DRD1KMT2AALDH1A1SMN1; SMN2
SCHEMBL2171861 0.83 DRD1 (0.54) DRD1
SCHEMBL21734394 0.80 DRD1 (0.83) DRD1
SCHEMBL21734396 0.79 DRD1 (0.49) DRD1ALDH1A1SMN1; SMN2
SCHEMBL2544893 0.78 DRD1 (0.51) DRD1
SCHEMBL21734356 0.77 DRD1 (0.74) DRD1
SCHEMBL2352234 0.74 DRD1 (0.56) DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020034477-A1 POROUS ORGANIC CAGE LIGAND CONTAINING P AND N, PREPARATION THEREFOR AND USE THEREOF 中国科学院大连化学物理研究所 2020-02-20 WO disclosed