SCHEMBL21736792

SCHEMBL21736792

CCc1ccc(N2CCCC2)cc1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.49
TP53BP1 Q12888 1/20 0.49
L3MBTL3 Q96JM7 1/20 0.49
MAPT P10636 7/20 0.49
ALDH1A1 P00352 2/20 0.49
GFER P55789 1/20 0.49
SMN1; SMN2 Q16637 4/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
LMNA P02545 2/20 0.48
THRB P10828 1/20 0.47
MAPK1 P28482 1/20 0.47
HTT P42858 1/20 0.47
ALOX15 P16050 1/20 0.45
HSD17B10 Q99714 1/20 0.45
EPHX2 P34913 2/20 0.43
NR1H4 Q96RI1 2/20 0.43
ADRB1 P08588 1/20 0.43
ALOX12 P18054 1/20 0.42
DRD4 P21917 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12875640 0.98 MEN1 (0.50) L3MBTL1TP53BP1L3MBTL3MAPTALDH1A1
SCHEMBL20884918 0.86 KDM4E (0.51) L3MBTL1MAPTALDH1A1GFERSMN1; SMN2
SCHEMBL12845388 0.85 GRM2 (0.48) L3MBTL1MAPTALDH1A1MEN1KMT2A
SCHEMBL5018022 0.81 L3MBTL1 (0.48) L3MBTL1TP53BP1L3MBTL3MAPTALDH1A1
SCHEMBL7916691 0.81 DRD4 (0.53) L3MBTL1TP53BP1L3MBTL3MAPTALDH1A1
SCHEMBL21736813 0.80 HPGD (0.53) L3MBTL1MAPTALDH1A1GFERSMN1; SMN2
SCHEMBL5724958 0.79 NOTUM (0.60) L3MBTL1TP53BP1L3MBTL3MAPTALDH1A1
SCHEMBL21737191 0.79 MAPT (0.45) L3MBTL1MAPTALDH1A1SMN1; SMN2MEN1
SCHEMBL1599647 0.79 MAPT (0.45) L3MBTL1MAPTALDH1A1SMN1; SMN2MEN1
SCHEMBL21736865 0.79 HPGD (0.55) L3MBTL1MAPTALDH1A1GFERSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611165-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed