SCHEMBL21737252

SCHEMBL21737252

C#CCOc1cccc(OC)c1N(C)C

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.41
CYP3A4 P08684 1/20 0.40
CYP2A6 P11509 1/20 0.40
MAPT P10636 1/20 0.39
MAOB P27338 5/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MAOA P21397 2/20 0.37
PDE4B Q07343 2/20 0.37
CA12 O43570 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
EGFR P00533 1/20 0.36
BCHE P06276 1/20 0.36
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
HTR7 P34969 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9634997 0.80 CA1 (0.52) DRD2CYP3A4MAPTSMN1; SMN2CA12
SCHEMBL29679041 0.78 CA12 (0.54) DRD2MAPTMAOBSMN1; SMN2MAOA
SCHEMBL6811036 0.78 CA12 (0.54) DRD2MAPTMAOBSMN1; SMN2MAOA
SCHEMBL4090880 0.77 SMN1; SMN2 (0.50) DRD2CYP3A4CYP2A6MAPTMAOB
SCHEMBL16378462 0.77 IDO1 (0.43) DRD2CYP3A4CYP2A6MAPTMAOB
SCHEMBL5685999 0.77 SMN1; SMN2 (0.59) DRD2CYP3A4CYP2A6MAPTSMN1; SMN2
SCHEMBL21719143 0.73 CYP3A4 (0.40) DRD2CYP3A4CYP2A6MAPTMAOB
SCHEMBL19616353 0.72 MAPT (0.48) CYP3A4CYP2A6MAPTMAOBMAOA
SCHEMBL30663731 0.71 MAPT (0.56) DRD2CYP3A4CYP2A6MAPTMAOB
SCHEMBL10347560 0.71 MAPT (0.56) DRD2CYP3A4CYP2A6MAPTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611165-B1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2023-08-16 EP disclosed
EP-3611165-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed