Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685999 | 0.89 | SMN1; SMN2 (0.59) | SMN1; SMN2CA12CA2CA9CYP3A4 | |
| SCHEMBL7265106 | 0.84 | TDP1 (0.40) | SMN1; SMN2CA12CA2CA9CYP3A4 | |
| SCHEMBL27584259 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2CA12CA2CA9CYP3A4 | |
| SCHEMBL29679041 | 0.82 | CA12 (0.54) | SMN1; SMN2CA12CA2CA9MAPT | |
| SCHEMBL6811036 | 0.82 | CA12 (0.54) | SMN1; SMN2CA12CA2CA9MAPT | |
| SCHEMBL3198497 | 0.82 | CYP3A4 (0.49) | SMN1; SMN2CYP3A4CYP2A6MAPTMAPK1 | |
| SCHEMBL16378462 | 0.81 | IDO1 (0.43) | SMN1; SMN2CA12CA2CA9CYP3A4 | |
| SCHEMBL2641374 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2CA12CA2CA9MAPK1 | |
| SCHEMBL5722457 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2CA12CA2CA9MAPK1 | |
| SCHEMBL17274855 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2CA12CA2CA9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | HSD3B1, HSD3B2, HSD11B1 | SMN1; SMN2 4801/4885CA12 1857/4885CA2 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.