SCHEMBL2173771

SCHEMBL2173771

CCN(CC)S(=O)(=O)c1ccc(Oc2c(C)c(CC(=O)O)cc3ccc(F)cc23)cc1.Cc1c(CC(=O)O)cc2ccc(F)cc2c1Oc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2171905 0.94 PTGDR2 (0.64) PTGDR2
SCHEMBL2172748 0.93 PTGDR2 (0.63) PTGDR2
SCHEMBL2172522 0.89 PTGDR2 (0.72) PTGDR2
SCHEMBL2172269 0.86 PTGDR2 (0.73) PTGDR2
SCHEMBL2173775 0.86 PTGDR2 (0.44) PTGDR2
SCHEMBL2172059 0.83 PTGDR2 (0.62) PTGDR2
SCHEMBL2173963 0.83 PTGDR2 (0.61) PTGDR2
SCHEMBL2171793 0.80 PTGDR2 (0.58) PTGDR2
SCHEMBL2171907 0.79 PTGDR2 (0.47) PTGDR2
SCHEMBL2171442 0.78 PTGDR2 (0.59) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346819-A1 NAPHTHYLACETIC ACIDS F. Hoffmann-La Roche AG (CH) 2011-07-27 EP disclosed