Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2173775 | 0.94 | PTGDR2 (0.44) | PTGDR2MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL2171905 | 0.85 | PTGDR2 (0.64) | PTGDR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL2173771 | 0.79 | PTGDR2 (0.59) | PTGDR2 | |
| SCHEMBL2172269 | 0.77 | PTGDR2 (0.73) | PTGDR2 | |
| SCHEMBL2172522 | 0.75 | PTGDR2 (0.72) | PTGDR2 | |
| SCHEMBL14837773 | 0.72 | PTGDR2 (0.63) | PTGDR2 | |
| SCHEMBL2174482 | 0.71 | PTGDR2 (0.38) | PTGDR2 | |
| SCHEMBL2172748 | 0.71 | PTGDR2 (0.63) | PTGDR2 | |
| SCHEMBL2172059 | 0.70 | PTGDR2 (0.62) | PTGDR2KMT2ALMNA | |
| SCHEMBL2173963 | 0.70 | PTGDR2 (0.61) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346819-A1 | NAPHTHYLACETIC ACIDS | F. Hoffmann-La Roche AG (CH) | 2011-07-27 | — | — | EP | claimed |