Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.73 |
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.73 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16557026 | 1.00 | CD274 (0.73) | CD274VSIRPDCD1LG2PDCD1TGFBR1 | |
| SCHEMBL16557050 | 0.92 | VSIR (0.62) | CD274VSIRPDCD1LG2PDCD1TGFBR1 | |
| SCHEMBL24058483 | 0.91 | VSIR (0.68) | CD274VSIRPDCD1LG2PDCD1CA2 | |
| SCHEMBL18078247 | 0.91 | VSIR (0.68) | CD274VSIRPDCD1LG2PDCD1CA2 | |
| SCHEMBL18078208 | 0.90 | VSIR (0.59) | CD274VSIRPDCD1LG2TGFBR1CA2 | |
| SCHEMBL24058475 | 0.90 | CD274 (0.70) | CD274VSIRPDCD1LG2PDCD1 | |
| SCHEMBL24595311 | 0.90 | VSIR (0.67) | CD274VSIRPDCD1LG2 | |
| SCHEMBL18078134 | 0.90 | VSIR (0.67) | CD274VSIRPDCD1LG2 | |
| SCHEMBL18719759 | 0.90 | CD274 (0.69) | CD274VSIRPDCD1LG2PDCD1 | |
| SCHEMBL16557044 | 0.89 | VSIR (0.59) | CD274VSIRPDCD1LG2TGFBR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3363790-B1 | 1,2,4-OXADIAZOLE DERIVATIVES AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2020-02-19 | — | — | EP | disclosed |