Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 4/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23475169 | 1.00 | BTK (0.50) | BTKKMT2AL3MBTL1CTSKCA1 | |
| SCHEMBL29676115 | 1.00 | BTK (0.50) | BTKKMT2AL3MBTL1CTSKCA1 | |
| SCHEMBL1116704 | 0.85 | BTK (0.54) | BTKKMT2AL3MBTL1CTSKCA1 | |
| SCHEMBL962474 | 0.85 | BTK (0.54) | BTKKMT2AL3MBTL1CTSKCA1 | |
| SCHEMBL29676411 | 0.85 | BTK (0.54) | BTKKMT2AL3MBTL1CTSKCA1 | |
| SCHEMBL31327089 | 0.83 | CTSK (0.51) | BTKKMT2AL3MBTL1CTSKCA1 | |
| SCHEMBL29498425 | 0.79 | BTK (0.55) | BTKKMT2AL3MBTL1CTSKCA1 | |
| SCHEMBL21631816 | 0.79 | BTK (0.55) | BTKKMT2AL3MBTL1CTSKCA1 | |
| SCHEMBL4321226 | 0.79 | BTK (0.59) | BTKKMT2AL3MBTL1CTSKCA1 | |
| SCHEMBL747015 | 0.79 | BTK (0.51) | BTKKMT2AL3MBTL1CTSKCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035464-A1 | NOVEL SULFONAMIDEUREA COMPOUNDS | INFLAZOME LIMITED (IE) | 2020-02-20 | — | — | WO | disclosed |