Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | PBK | Q96KB5 | 5/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22857559 | 0.85 | CPN1 (0.46) | CPN1CPB2PBKCHEK1TLR9 | |
| SCHEMBL22857495 | 0.85 | CPN1 (0.46) | CPN1CPB2PBKCHEK1TLR9 | |
| SCHEMBL22752000 | 0.82 | CPN1 (0.44) | CPN1CPB2PBKCHEK1TLR9 | |
| SCHEMBL12413663 | 0.82 | CPN1 (0.44) | CPN1CPB2PBKCHEK1TLR9 | |
| SCHEMBL22752189 | 0.82 | CPN1 (0.44) | CPN1CPB2PBKCHEK1TLR9 | |
| SCHEMBL3214410 | 0.82 | TSHR (0.49) | EPHX1KMT2ACYP2D6TSHR | |
| SCHEMBL8246570 | 0.80 | TDP1 (0.50) | KMT2ACYP2D6TSHRDPP4FAP | |
| SCHEMBL16509283 | 0.77 | EPHX1 (0.44) | CPN1CPB2PBKCHEK1EPHX1 | |
| SCHEMBL12507030 | 0.77 | EPHX1 (0.44) | CPN1CPB2PBKCHEK1EPHX1 | |
| SCHEMBL13212506 | 0.77 | PBK (0.45) | CPN1CPB2PBKCHEK1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210221812-A1 | MATRINE a-KETOAMINE COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI XINGYE PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2021-07-22 | — | — | US | disclosed |
| WO-2020035010-A1 | MATRINE α-KETOAMINE COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海星叶医药科技有限公司 | 2020-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210221812-A1 | MATRINE a-KETOAMINE COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | KLKB1, TNF, KMO | CPN1 4322/4885CPB2 3057/4885PBK 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.