Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Thiophene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiophene SCHEMBL9249680 | 1.00 | — | — | |
| Thiophene SCHEMBL10751274 | 1.00 | — | — | |
| Iodide SCHEMBL28772309 | 0.95 | TP53 (0.30) | — | |
| Iodide SCHEMBL29660997 | 0.95 | TP53 (0.30) | — | |
| Thiophene SCHEMBL225198 | 0.94 | — | — | |
| Thiophene SCHEMBL243 | 0.94 | — | — | |
| Thiophene SCHEMBL168628 | 0.94 | — | — | |
| Thiophene SCHEMBL8451885 | 0.89 | — | — | |
| Thiophene SCHEMBL2852585 | 0.89 | — | — | |
| Thiophene SCHEMBL1222753 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117998952-A | Perovskite photoelectric device, preparation method thereof and optical device | 清华大学 | 2024-05-07 | — | — | CN | claimed |
| CN-119300606-A | Trans perovskite solar cell and preparation method thereof | 天合光能股份有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-117998952-A | Perovskite photoelectric device, preparation method thereof and optical device | 清华大学 | 2024-05-07 | — | — | CN | disclosed |
| CN-117466745-A | Method for synthesizing arylamine compound by using photochemical manganese as catalyst | 陕西师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-110016010-B | Preparation method of thiophenecarboxaldehyde compound | 兰州大学 | 2021-09-14 | — | — | CN | disclosed |
| CN-108299140-B | Synthetic method of biaryl compound | 济南大学 | 2020-12-15 | — | — | CN | disclosed |
| CN-110333645-A | Photoresist comprising a variety of raw sour immunomodulator compounds | 罗门哈斯电子材料有限公司 | 2019-10-15 | — | — | CN | disclosed |
| CN-110016010-A | A kind of preparation method of novel thiophenecarboxaldehyde class compound | 兰州大学 | 2019-07-16 | — | — | CN | disclosed |
| CN-109970630-A | A kind of two-photon fluorescence probe and its preparation method and application of energy targetted mitochondria | 四川大学 | 2019-07-05 | — | — | CN | disclosed |
| CN-103676477-B | Give birth to acid immunomodulator compounds and include its photoresist | 罗门哈斯电子材料有限公司 | 2018-05-08 | — | — | CN | disclosed |
| CN-103676477-A | Acid generator compounds and photoresists comprising same | ROHM & HAAS ELECT MAT | 2014-03-26 | — | — | CN | disclosed |
| CN-103004012-A | Electrolyte for photoelectric conversion element, photoelectric conversion element using the electrolyte, and dye-sensitized solar cell using the electrolyte | YOKOHAMA RUBBER CO LTD | 2013-03-27 | — | — | CN | disclosed |
| US-20120252868-A1 | NOVEL MEANS AND METHODS FOR THE TREATMENT OF HEARING LOSS AND PHANTOM HEARING | UNIVERSITY OF GENEVA (CH) | 2012-10-04 | — | — | US | disclosed |
| CN-102597277-A | Ionic liquid solvents of the perhalide type for metals and metal compounds | PETROLIAM NASIONAL BERHAD | 2012-07-18 | — | — | CN | disclosed |
| CN-102449204-A | Electrodeposition of elemental zinrconium | ASTRON ADVANCED MATERIALS LTD | 2012-05-09 | — | — | CN | disclosed |
| US-8088359-B2 | Means and methods of using a NADPH oxidase inhibitor for the treatment of hearing loss and phantom hearing | UNIVERSITY OF GENEVA (CH) | 2012-01-03 | — | — | US | disclosed |
| US-20090263323-A1 | Novel means and methods for the treatment of hearing loss and phantom hearing | UNIVERSITY OF GENEVA | 2009-10-22 | — | — | US | disclosed |
| EP-1923702-A2 | Novel means and methods for the treatment of hearing loss and phantom hearing | University of Geneva (CH) | 2008-05-21 | — | — | EP | disclosed |
| EP-1766390-A2 | NOVEL MEANS AND METHODS FOR THE TREATMENT OF HEARING LOSS AND PHANTOM HEARING | University of Geneva (CH) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005119251-A2 | NOVEL MEANS AND METHODS FOR THE TREATMENT OF HEARING LOSS AND PHANTOM HEARING | UNIVERSITY OF GENEVA (CH) | 2005-12-15 | — | — | WO | disclosed |