Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28772309 | 1.00 | TP53 (0.30) | TP53TSHR | |
| Benzene SCHEMBL28210283 | 0.95 | TP53 (0.33) | TP53TSHR | |
| Benzene SCHEMBL1975626 | 0.95 | TP53 (0.33) | TP53TSHR | |
| Benzene SCHEMBL28274157 | 0.95 | TP53 (0.33) | TP53TSHR | |
| SCHEMBL40554 | 0.95 | — | — | |
| Thiophene SCHEMBL9249680 | 0.95 | — | — | |
| Thiophene SCHEMBL10751274 | 0.95 | — | — | |
| Benzene SCHEMBL15255212 | 0.95 | TP53 (0.33) | TP53TSHR | |
| Thiophene SCHEMBL217403 | 0.95 | — | — | |
| Benzene SCHEMBL28269956 | 0.95 | TP53 (0.33) | TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250325557-A1 | 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | WISTA LABORATORIES LTD. (SG) | 2025-10-23 | — | — | US | disclosed |
| US-12324810-B2 | 3, 7-diamino-10H-phenothiazine salts and their use | WISTA LABORATORIES LTD. (SG) | 2025-06-10 | — | — | US | disclosed |
| US-20240245700-A1 | 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | WISTA LABORATORIES LTD. (SG) | 2024-07-25 | — | — | US | disclosed |
| US-11951110-B2 | 3, 7-diamino-10H-phenothiazine salts and their use | WISTA LABORATORIES LTD. (SG) | 2024-04-09 | — | — | US | disclosed |
| US-11344558-B2 | 3, 7-diamino-10H-phenothiazine salts and their use | WISTA LABORATORIES LTD. (SG) | 2022-05-31 | — | — | US | disclosed |
| US-20220152038-A1 | 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | WISTA LABORATORIES LTD. (SG) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325557-A1 | 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | PSEN1, PSEN2, APP | TP53 1630/4885TSHR 1453/4885 |
| US-12324810-B2 | 3, 7-diamino-10H-phenothiazine salts and their use | PSEN1, PSEN2, APP | TP53 1921/4885TSHR 1169/4885 |
| US-11951110-B2 | 3, 7-diamino-10H-phenothiazine salts and their use | PSEN1, PSEN2, APP | TP53 1630/4885TSHR 1453/4885 |
| US-11344558-B2 | 3, 7-diamino-10H-phenothiazine salts and their use | PSEN1, PSEN2, APP | TP53 1630/4885TSHR 1453/4885 |
| US-20220152038-A1 | 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | PSEN1, PSEN2, APP | TP53 1894/4885TSHR 1072/4885 |
| US-20240245700-A1 | 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | PSEN1, PSEN2, APP | TP53 1921/4885TSHR 1169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.