Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3156546 | 0.88 | FBP1 (0.84) | FBP1 | |
| SCHEMBL2932042 | 0.87 | FBP1 (0.82) | FBP1 | |
| SCHEMBL2178259 | 0.86 | FBP1 (1.00) | FBP1 | |
| SCHEMBL2175253 | 0.85 | FBP1 (0.80) | FBP1 | |
| SCHEMBL2178055 | 0.84 | FBP1 (1.00) | FBP1 | |
| SCHEMBL2174038 | 0.84 | FBP1 (0.80) | FBP1 | |
| SCHEMBL2176079 | 0.84 | FBP1 (0.86) | FBP1 | |
| SCHEMBL2175098 | 0.83 | FBP1 (0.55) | FBP1 | |
| SCHEMBL2176373 | 0.82 | FBP1 (0.83) | FBP1 | |
| SCHEMBL2175610 | 0.82 | FBP1 (0.79) | FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973051-B2 | Aminothiazoles as FBPase inhibitors for diabetes | HOFFMAN-LA ROCHE INC. (US) | 2011-07-05 | — | — | US | claimed |
| US-7973051-B2 | Aminothiazoles as FBPase inhibitors for diabetes | HOFFMAN-LA ROCHE INC. (US) | 2011-07-05 | — | — | US | disclosed |