SCHEMBL2174100

SCHEMBL2174100

CC(C(N)=O)N1CCCC1=O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.64
CA12 O43570 1/20 0.64
CA1 P00915 1/20 0.64
CA2 P00918 1/20 0.64
CA3 P07451 1/20 0.64
CA4 P22748 1/20 0.64
CA6 P23280 1/20 0.64
CA5A P35218 1/20 0.64
CA7 P43166 1/20 0.64
CA9 Q16790 1/20 0.64
CA13 Q8N1Q1 1/20 0.64
CA14 Q9ULX7 1/20 0.64
CA5B Q9Y2D0 1/20 0.64
TSHR P16473 1/20 0.43
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM5 P08912 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
PIK3CD O00329 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2617943 1.00 LMNA (0.64) LMNACA12CA1CA2CA3
SCHEMBL14419736 0.94 LMNA (0.57) LMNACA12CA1CA2CA3
SCHEMBL14419799 0.94 LMNA (0.57) LMNACA12CA1CA2CA3
Trifluoroacetic Acid SCHEMBL4471386 0.89 LMNA (0.56) LMNACA12CA1CA2CA3
SCHEMBL13788522 0.82 LMNA (0.51) LMNACA12CA1CA2CA3
SCHEMBL951298 0.82 LMNA (0.51) LMNACA12CA1CA2CA3
SCHEMBL10959845 0.82 LMNA (0.51) LMNACA12CA1CA2CA3
SCHEMBL3713795 0.81 LMNA (0.60) LMNACA12CA1CA2CA3
Urea SCHEMBL14776158 0.81 LMNA (0.59) LMNACA12CA1CA2CA3
SCHEMBL2617906 0.79 LMNA (0.45) LMNACA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115724782-A Preparation and removal method of levetiracetam impurities 浙江华海药业股份有限公司 2023-03-03 CN claimed
CN-1272841-A Novel lactam metalloprotease inhibitors DU PONT PHARM CO (US) 2000-11-08 CN claimed
US-4115579-A 2-OXO-1-PYRROLIDINEACETAMIDE, 2-(2-OXOPYRROLIDINO)PROPIONAMIDE OR 2-(2-OXOPYRROLIDINO)BUTYRAMIDE U C B, SOCIETE ANONYME (BE) 1978-09-19 US claimed
US-20250382265-A1 MODIFIED AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND SELECTED PSYCHIATRIC DISORDERS UNIV JAGIELLONSKI (PL) 2025-12-18 US disclosed
US-20250382265-A1 MODIFIED AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND SELECTED PSYCHIATRIC DISORDERS UNIV JAGIELLONSKI (PL) 2025-12-18 US disclosed
EP-4623910-A3 MODIFIED AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND SELECTED PSYCHIATRIC DISORDERS UNIWERSYTET JAGIELLONSKI (PL) 2025-12-10 EP disclosed
EP-4623910-A2 MODIFIED AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND SELECTED PSYCHIATRIC DISORDERS UNIWERSYTET JAGIELLONSKI (PL) 2025-10-01 EP disclosed
EP-4623910-A2 MODIFIED AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND SELECTED PSYCHIATRIC DISORDERS UNIWERSYTET JAGIELLONSKI (PL) 2025-10-01 EP disclosed
US-12421189-B2 Modified amino acid derivatives for the treatment of neurological diseases and selected psychiatric disorders UNIWERSYTET JAGIELLONSKI (PL) 2025-09-23 US disclosed
US-12421189-B2 Modified amino acid derivatives for the treatment of neurological diseases and selected psychiatric disorders UNIWERSYTET JAGIELLONSKI (PL) 2025-09-23 US disclosed
EP-3956310-B1 MODIFIED AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND SELECTED PSYCHIATRIC DISORDERS UNIV JAGIELLONSKI (PL) 2025-08-06 EP disclosed
US-7973047-B2 Beta-Secretase modulators and methods of use AMGEN INC. (US) 2011-07-05 US disclosed
WO-2010132693-A2 OLIGOMER-CONTAINING PYRROLIDINE COMPOUNDS NEKTAR THERAPEUTICS (US) 2010-11-18 WO disclosed
WO-2010132693-A2 OLIGOMER-CONTAINING PYRROLIDINE COMPOUNDS NEKTAR THERAPEUTICS (US) 2010-11-18 WO disclosed
US-20100222338-A1 BETA-SECRETASE MODULATORS AND METHODS OF USE AMGEN INC. 2010-09-02 US disclosed
CN-1272841-A Novel lactam metalloprotease inhibitors DU PONT PHARM CO (US) 2000-11-08 CN disclosed
CN-1268111-A Iodopropagylamine compounds, and industrial antimicrobial and antifungal agents, algicides, and antifouling agents containing the same NISSAN CHEMICAL IND LTD (JP) 2000-09-27 CN disclosed
US-4908202-A Administering known dosage of piracetam to subject, withdrawing blood samples at spaced time intervals, measuring differences in piracetam present in samples CASSELLA AKTIENGESELLSCHAFT (DE) 1990-03-13 US disclosed
US-4115579-A 2-OXO-1-PYRROLIDINEACETAMIDE, 2-(2-OXOPYRROLIDINO)PROPIONAMIDE OR 2-(2-OXOPYRROLIDINO)BUTYRAMIDE U C B, SOCIETE ANONYME (BE) 1978-09-19 US disclosed
US-4115579-A 2-OXO-1-PYRROLIDINEACETAMIDE, 2-(2-OXOPYRROLIDINO)PROPIONAMIDE OR 2-(2-OXOPYRROLIDINO)BUTYRAMIDE U C B, SOCIETE ANONYME (BE) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100222338-A1 BETA-SECRETASE MODULATORS AND METHODS OF USE BACE1, BACE2, APP LMNA 705/4885CA12 2744/4885CA1 290/4885
US-20250382265-A1 MODIFIED AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND SELECTED PSYCHIATRIC DISORDERS SLC1A2, GRIN2A, GRIN2D LMNA 1231/4885CA12 4480/4885CA1 1105/4885
US-12421189-B2 Modified amino acid derivatives for the treatment of neurological diseases and selected psychiatric disorders SLC1A2, GRIN2A, GRIN2D LMNA 1231/4885CA12 4480/4885CA1 1105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.