Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.33 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27834052 | 0.98 | DUT (0.40) | DUTHTR2AHRH1TDP1L3MBTL1 | |
| SCHEMBL11897958 | 0.84 | DUT (0.39) | DUTHTR2ATDP1L3MBTL1IDO1 | |
| SCHEMBL17760802 | 0.84 | IDO1 (0.46) | TDP1L3MBTL1IDO1 | |
| SCHEMBL1629726 | 0.84 | IGF1R (0.41) | DUTHRH1 | |
| SCHEMBL16307320 | 0.84 | IDO1 (0.46) | TDP1L3MBTL1IDO1 | |
| SCHEMBL6558611 | 0.84 | IDO1 (0.46) | TDP1L3MBTL1IDO1 | |
| SCHEMBL16784080 | 0.84 | IDO1 (0.46) | TDP1L3MBTL1IDO1 | |
| SCHEMBL23301487 | 0.83 | DUT (0.34) | DUTHTR2AHRH1L3MBTL1 | |
| SCHEMBL1627500 | 0.83 | DUT (0.40) | DUTTDP1TNNC1SGPL1S1PR4 | |
| SCHEMBL1627173 | 0.83 | DUT (0.40) | DUTSPHK2TNNC1SGPL1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035049-A1 | DEGRADATION AGENTS FOR CYCLIN DEPENDENT KINASE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 中国科学院上海药物研究所 | 2020-02-20 | — | — | WO | disclosed |