Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | GPR4 | P46093 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1626358 | 0.90 | PTGER4 (0.55) | PTGER4GPR4MEN1KMT2ACYP1A2 | |
| SCHEMBL30224999 | 0.90 | PTGER4 (0.55) | PTGER4GPR4MEN1KMT2ACYP1A2 | |
| SCHEMBL1624672 | 0.90 | PTGER4 (0.55) | PTGER4GPR4MEN1KMT2AFAAH | |
| SCHEMBL30513699 | 0.90 | PTGER4 (0.57) | PTGER4GPR4MEN1KMT2AFAAH | |
| SCHEMBL1624736 | 0.90 | PTGER4 (0.57) | PTGER4GPR4MEN1KMT2AFAAH | |
| Hydrochloric Acid SCHEMBL1999779 | 0.88 | PTGER4 (0.54) | PTGER4GPR4MEN1KMT2ACYP1A2 | |
| SCHEMBL23876875 | 0.87 | PTGER4 (0.51) | PTGER4MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL21741601 | 0.87 | PTGER4 (0.61) | PTGER4GPR4ALDH1A1CYP1A2ATM | |
| SCHEMBL3946713 | 0.86 | PTGER4 (0.52) | PTGER4GPR4MEN1KMT2AGRM5 | |
| SCHEMBL23876632 | 0.84 | PTGER4 (0.60) | PTGER4GPR4MEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020014465-A9 | POLYMORPHIC COMPOUNDS AND USES THEREOF | Arrys Therapeutics, Inc. (US) | 2020-02-20 | — | — | WO | disclosed |