Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GPR4 | P46093 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1624736 | 1.00 | PTGER4 (0.57) | PTGER4FAAHMEN1KMT2ATP53 | |
| SCHEMBL1624348 | 0.90 | PTGER4 (0.49) | PTGER4TP53MAPTESR1ESR2 | |
| SCHEMBL21741607 | 0.90 | PTGER4 (0.57) | PTGER4FAAHMEN1KMT2ATP53 | |
| SCHEMBL1624672 | 0.87 | PTGER4 (0.55) | PTGER4FAAHMEN1KMT2ATP53 | |
| SCHEMBL1626358 | 0.87 | PTGER4 (0.55) | PTGER4FAAHMEN1KMT2ATP53 | |
| SCHEMBL30224999 | 0.87 | PTGER4 (0.55) | PTGER4FAAHMEN1KMT2ATP53 | |
| SCHEMBL23876632 | 0.87 | PTGER4 (0.60) | PTGER4FAAHMEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL1999779 | 0.86 | PTGER4 (0.54) | PTGER4FAAHMEN1KMT2AGPR4 | |
| SCHEMBL1626154 | 0.86 | PTGER4 (0.46) | PTGER4FAAHTP53MAPT | |
| SCHEMBL21741601 | 0.85 | PTGER4 (0.61) | PTGER4FAAHTP53MAPTGPR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496274-A | Preparation method of EP4 receptor antagonist | 江苏天和制药有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-116496274-A | Preparation method of EP4 receptor antagonist | 江苏天和制药有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116496274-A | Preparation method of EP4 receptor antagonist | 江苏天和制药有限公司 | 2023-07-28 | — | — | CN | disclosed |