SCHEMBL21742919 — predicted protein targets

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	KCNA3	P22001	1/20	0.34

▸	HTR2A	P28223	6/20	0.33

▸	HTR2C	P28335	6/20	0.33

▸	HTR2B	P41595	5/20	0.33

▸	SLC6A2	P23975	2/20	0.30

▸	SLC6A4	P31645	2/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21742716	1.00	KCNA3 (0.34)	KCNA3HTR2AHTR2CHTR2BSLC6A2
SCHEMBL23521674	0.80	SLC6A2 (0.50)	HTR2AHTR2CHTR2BSLC6A2SLC6A4
SCHEMBL21742882	0.80	SLC6A2 (0.50)	HTR2AHTR2CHTR2BSLC6A2SLC6A4
SCHEMBL30788068	0.80	SLC6A2 (0.50)	HTR2AHTR2CHTR2BSLC6A2SLC6A4
Hydrochloric Acid SCHEMBL6712642	0.66	SLC6A4 (0.65)	HTR2AHTR2CHTR2BSLC6A2SLC6A4
Hydrochloric Acid SCHEMBL6712640	0.66	SLC6A4 (0.65)	HTR2AHTR2CHTR2BSLC6A2SLC6A4
Hydrochloric Acid SCHEMBL5869202	0.66	SLC6A4 (0.65)	HTR2AHTR2CHTR2BSLC6A2SLC6A4
SCHEMBL3791653	0.65	KCNA3 (0.47)	KCNA3HTR2AHTR2CHTR2BSLC6A2
SCHEMBL6267824	0.64	KCNA3 (0.49)	KCNA3HTR2AHTR2CHTR2BSLC6A2
SCHEMBL5079373	0.64	SLC6A4 (0.56)	SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020035070-A1	3-ARYLOXY-3-ARYL-PROPYLAMINE COMPOUND AND USES THEREOF	漳州片仔癀药业股份有限公司	2020-02-20	—	—	WO	disclosed