Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 15/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28017684 | 0.83 | SLC6A2 (0.68) | SLC6A4SLC6A2SLC6A3HTR1B | |
| SCHEMBL541162 | 0.83 | SLC6A2 (0.68) | SLC6A4SLC6A2SLC6A3HTR1B | |
| SCHEMBL29974656 | 0.82 | SLC6A2 (0.38) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL21742901 | 0.82 | SLC6A2 (0.38) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL23521648 | 0.82 | SLC6A2 (0.38) | SLC6A4SLC6A2SLC6A3 | |
| Bromide SCHEMBL6903611 | 0.82 | SLC6A2 (0.66) | SLC6A4SLC6A2SLC6A3HTR1B | |
| Cadaverine Tartrate SCHEMBL3757 | 0.76 | SLC6A4 (0.64) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5083226 | 0.74 | SLC6A2 (0.57) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17278119 | 0.74 | SLC6A2 (0.63) | SLC6A4SLC6A2SLC6A3HTR1B | |
| Oxalic Acid SCHEMBL8718092 | 0.72 | PPARG (0.44) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133884-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-11-06 | — | — | WO | disclosed |