Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.45 |
| ▸ | CD44 | P16070 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21743757 | 0.85 | PLD1 (0.52) | SMN1; SMN2TLR9TLR7GAACYP3A4 | |
| SCHEMBL16485203 | 0.82 | CD44 (0.50) | TLR9TLR7CD44HTR2CHTR2A | |
| SCHEMBL21744394 | 0.82 | HTR2C (0.54) | CYP2D6CD44ALDH1A1KDM4ELMNA | |
| SCHEMBL21744250 | 0.80 | CHRM2 (0.52) | TLR9TLR7CYP3A4CYP2D6CHRM2 | |
| SCHEMBL1011153 | 0.78 | CD44 (0.49) | TLR9TLR7CYP3A4CYP2D6CD44 | |
| SCHEMBL21743762 | 0.78 | CD44 (0.45) | TLR9TLR7CYP3A4CYP2D6CXCR4 | |
| SCHEMBL21744598 | 0.78 | CD44 (0.45) | TLR9TLR7CYP2D6CXCR4CD44 | |
| SCHEMBL21744256 | 0.78 | DRD2 (0.47) | TLR9TLR7CXCR4CD44HTR2C | |
| SCHEMBL21744605 | 0.76 | CD44 (0.46) | TLR9TLR7GAACHRM2CHRM4 | |
| SCHEMBL21744697 | 0.76 | CD44 (0.46) | TLR9TLR7CYP3A4CYP2D6CD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | UNIV EMORY (US) | 2023-04-13 | — | — | US | disclosed |
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | EMORY UNIVERSITY | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | POLB 3104/4885SMN1; SMN2 4199/4885TLR9 138/4885 |
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | POLB 3104/4885SMN1; SMN2 4199/4885TLR9 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.