Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.37 |
| ▸ | PRKCH | P24723 | 2/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | PRKDC | P78527 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5880446 | 0.82 | HTR2C (0.46) | LRRK2HTR2CHTR2BHTR2APIK3CD | |
| SCHEMBL21744588 | 0.78 | CD44 (0.41) | HTR2CSLC6A2SLC6A4SLC6A3HTR2B | |
| SCHEMBL31354869 | 0.76 | HTR2C (0.48) | HTR2CHTR2BHTR2A | |
| SCHEMBL31354888 | 0.75 | HTR2C (0.45) | HTR2CHTR2BHTR2ACD44 | |
| SCHEMBL14863103 | 0.75 | HRH4 (0.47) | HTR2CHTR2A | |
| SCHEMBL31400414 | 0.70 | KMT2A (0.36) | LRRK2PIK3CDMTORCD44 | |
| SCHEMBL20025484 | 0.65 | ALDH1A1 (0.56) | PRKCQMAP4K1FFAR2SLC6A2SLC6A4 | |
| SCHEMBL10200468 | 0.64 | LRRK2 (0.43) | LRRK2HTR2CHTR2BHTR2A | |
| SCHEMBL20025468 | 0.64 | SLC6A2 (0.41) | LRRK2PRKCQMAP4K1PRKCHSLC6A2 | |
| SCHEMBL20025478 | 0.63 | LRRK2 (0.41) | LRRK2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | EMORY UNIVERSITY | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | LRRK2 1466/4885PRKCQ 907/4885MAP4K1 1473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.