Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174478 | 0.86 | PTGDR2 (0.53) | PTGDR2 | |
| SCHEMBL2172961 | 0.75 | PTGDR2 (0.54) | PTGDR2 | |
| SCHEMBL2172812 | 0.74 | PTGDR2 (0.64) | PTGDR2PTGS1PTGS2 | |
| SCHEMBL2172893 | 0.71 | PTGDR2 (0.56) | PTGDR2 | |
| SCHEMBL2171907 | 0.71 | PTGDR2 (0.47) | PTGDR2 | |
| SCHEMBL2173455 | 0.70 | PTGDR2 (0.59) | PTGDR2 | |
| SCHEMBL2173775 | 0.70 | PTGDR2 (0.44) | PTGDR2 | |
| SCHEMBL2171334 | 0.70 | PTGDR2 (0.54) | PTGDR2 | |
| SCHEMBL2171442 | 0.69 | PTGDR2 (0.59) | PTGDR2 | |
| SCHEMBL2172905 | 0.69 | PTGDR2 (0.64) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346819-A1 | NAPHTHYLACETIC ACIDS | F. Hoffmann-La Roche AG (CH) | 2011-07-27 | — | — | EP | disclosed |