Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 20/20 | 0.82 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.82 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.82 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.82 |
| ▸ | CHRM5 | P08912 | 9/20 | 0.82 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.82 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21744151 | 0.92 | CXCR4 (0.81) | CXCR4CYP2D6CHRM2CHRM4CHRM5 | |
| SCHEMBL24975308 | 0.91 | CXCR4 (0.85) | CXCR4CYP2D6CHRM2CHRM4CHRM5 | |
| SCHEMBL20483199 | 0.90 | CXCR4 (1.00) | CXCR4CYP2D6CHRM2CHRM4CHRM5 | |
| SCHEMBL20483202 | 0.90 | CXCR4 (1.00) | CXCR4CYP2D6CHRM2CHRM4CHRM5 | |
| SCHEMBL21743938 | 0.89 | CXCR4 (0.82) | CXCR4CYP2D6CHRM2CHRM4CHRM5 | |
| SCHEMBL21744551 | 0.89 | CXCR4 (0.82) | CXCR4CYP2D6CHRM2CHRM4CHRM5 | |
| SCHEMBL21744546 | 0.88 | CXCR4 (0.79) | CXCR4CYP2D6CHRM2CHRM4CHRM5 | |
| SCHEMBL21744834 | 0.87 | CXCR4 (0.81) | CXCR4CYP2D6CHRM2CHRM4CHRM5 | |
| SCHEMBL21744150 | 0.86 | CXCR4 (0.63) | CXCR4CYP2D6CHRM2CHRM4CHRM5 | |
| SCHEMBL21744148 | 0.85 | CXCR4 (0.81) | CXCR4CYP2D6CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | EMORY UNIVERSITY | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | CXCR4 1/4885CYP2D6 4404/4885CHRM2 2559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.